SciELO - Scientific Electronic Library Online

 
vol.17 issue2In vitro antimicrobial activity of the extract of Abarema cochliocarpos (Gomes) Barneby & GrimesAntimicrobial activity of essential oils produced by Baccharis dracunculifolia D.C. and Baccharis uncinella D.C. (Asteraceae) author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Revista Brasileira de Farmacognosia

Print version ISSN 0102-695X

Abstract

DEUSCHLE, Régis A. N. et al. Fractionation of dichlorometane extract from Senecio desiderabilis Vellozo and evaluation of the antimicrobial activity. Rev. bras. farmacogn. [online]. 2007, vol.17, n.2, pp. 220-223. ISSN 0102-695X.  http://dx.doi.org/10.1590/S0102-695X2007000200015.

The present work describes the evaluation of the antimicrobial activity of a sesquiterpene fraction obtained from CH2Cl2 extract of Senecio desiderabilis Vellozo (Asteraceae), and of germacrene D isolated from it. The sesquiterpene fraction and the isolated substance were obtained by column chromatography and analysed by GC-MS. Substance identification was carried out by NMR. The antimicrobial activity was assayed by broth microdilution method, as preconized by NCCLS in the documents M27-A for yeasts and M7-A4 for bacteria. The sesquiterpene fraction showed moderated antimicrobial activity, and germacrene D did not inhibit the tested microorganisms.

Keywords : Senecio desiderabilis; Asteraceae; antimicrobial activity; sesquiterpene; germacrene D.

        · abstract in Portuguese     · text in Portuguese     · pdf in Portuguese