Abstract

SERAFIN, Claudia et al. Evaluation of the antimicrobial effects of Plinia glomerata (Myrtaceae). Rev. bras. farmacogn. [online]. 2007, vol.17, n.4, pp. 578-582. ISSN 0102-695X.  http://dx.doi.org/10.1590/S0102-695X2007000400017.

Plinia glomerata, commonly known as " yellow jaboticaba" or " cabelluda" occurs widely in south of Brazil. This work evaluated the antimicrobial properties of the extracts, fractions and isolated compounds of this plant against pathogenic microorganisms, bacteria and fungi. The minimal inhibitory concentration (MIC) was determined through the method of dilution in agar. The ethyl acetate (EtOAc) and aqueous fractions demonstrated the best activity against Staphylococcus aureus. The aqueous fraction also exhibited good activity against Escherichia coli. The pure substances 3,4,3’-trimethoxy-flavellagic-4’-O-glucose acid and 3,4,3’-trimethoxy-flavellagic acid were inactive up to 500 µg/mL. Regarding results against fungi, EA and EM extracts as well as AQ fraction showed good activity only against dermatophytes. The results suggest that P. glomerata produces active principles with antimicrobial activity, suggesting that other substances from the plant are acting against the microorganisms or the existence of synergic effects.

Keywords : Plinia glomerata; antimicrobial activity; 3,4,3’-trimethoxy-flavellagic-4’-O-glucose acid; 3,4,3’-trimethoxy-flavellagic acid.