Revista Brasileira de Farmacognosia
versión impresa ISSN 0102-695X
BARBOSA-FILHO, José M. et al. GC-MS analysis and cardiovascular activity of the essential oil of Ocotea duckei. Rev. bras. farmacogn. [online]. 2008, vol.18, n.1, pp. 37-41. ISSN 0102-695X. http://dx.doi.org/10.1590/S0102-695X2008000100009.
The essential oils obtained by steam distillation from the roots, stems, leaves and fruits of Ocotea duckei had their composition analyzed by GC-MS. The pharmacological activity of these oils was also evaluated showing significant cardiovascular effects. Forty-nine substances were identified, consisting of a complex mixture of monoterpenes (45%) and sesquiterpenes (55%). The fruits yielded (1.9%) more essential oil than the stems (1.0%), roots (0.8%) and leaves (0.7%). The main component in the oil of the leaves was trans-caryophyllene (60.54%), in the stem bark b-eudesmol (27.51%) and in the fruits, dl-limonene (30.12%). The predominant essential oil component in the roots was elemol (24.31%). In non-anaesthetized normotensive rats, the essential oils from different parts of Ocotea duckei (leaves, fruits, stem and roots) induced significant (p < 0.05) hypotension followed by bradycardia.
Palabras llave : Ocotea duckei; Lauraceae; essential oil; GC-MS analysis; cardiovascular activity.