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Cornoside and other constituents from the latex of Parahancornia amapa (Hub.) Ducke (Apocynaceae) a medicinal plant in Northern Brazil

Cornosídeo e outros constituintes do látex de Parahancornia amapa (Hub.) Ducke (Apocynaceae) uma planta medicinal no Norte do Brasil

Latex of Parahancornia amapa which is known as "amapa milk" in folk medicine was extracted with hexane, dichloromethane and methanol. From the hexane and dichloromethane were identified mixtures of 3-O-acyl lupeol esters such as identified previously. In the methanol extract, a large amount of carbohydrates, the phenylethanoid glucoside known as cornoside, other phenylethanoids derivatives and methylmyoinositol were identified. The analysis of IR, NMR and GC-LRMS of the natural compounds and tetra-acetylcornoside and comparison with literature data were used to identify the compounds.

Parahancornia amapa; amapá; phenylethanoids; carbohydrates; cornoside; lupeol esters


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