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Revista Brasileira de Farmacognosia

Print version ISSN 0102-695XOn-line version ISSN 1981-528X

Abstract

COUTINHO, Henrique D. M.; COSTA, José G. M.; SIQUEIRA-JUNIOR, José P.  and  LIMA, Edeltrudes O.. In vitro anti-staphylococcal activity of Hyptis martiusii Benth against methicillin-resistant Staphylococcus aureus: MRSA strains. Rev. bras. farmacogn. [online]. 2008, vol.18, suppl., pp.670-675. ISSN 0102-695X.  http://dx.doi.org/10.1590/S0102-695X2008000500005.

This is the first report about the antibacterial activity of Hyptis martiusii Benth. In this study the ethanol extract of H. martiusii was tested for its antimicrobial activity against strains of Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus. The growth of all bacterial strains tested was inhibited by the extract. The diameter of inhibition zones varied from 13 to 20 mm for the extract. The MIC and MBC values ranged from 128 to > 1024mg/mL and 256 to > 1024 mg/mL, respectively. It is therefore suggested that extracts from H. martiusii could be used as an anti-Staphylococcus agent. Compared with methicillin and gentamicin, the extract was more effective, being a promising antibacterial agent.

Keywords : Hyptis martiusii; Labiatae; anti-staphylococcal activity; antimicrobial activity.

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