SciELO - Scientific Electronic Library Online

vol.21 número4Antioxidant activities of Juniperus foetidissima essential oils against several oxidative systemsBioactivity of the compounds isolated from Blepharocalyx salicifolius índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados




Links relacionados


Revista Brasileira de Farmacognosia

versão impressa ISSN 0102-695X


GROSSO, Clara et al. Chemical composition and biological screening of Capsella bursa-pastoris. Rev. bras. farmacogn. [online]. 2011, vol.21, n.4, pp.635-643.  Epub 17-Jun-2011. ISSN 0102-695X.

Capsella bursa-pastoris (L.) Medik. (Brassicaceae) is a wild herb with high nutritional value that can be eaten raw or cooked. A metabolomic study was performed with different extracts of its aerial parts that were tested concerning their antiradical, acetylcholinesterase inhibitory and antibacterial activities. Phenolic compounds were identified and quantified by HPLC-DAD, organic acids and amino acids were determined by HPLC-UV, while free fatty acids and sterols were analysed by GC-ITMS. The vegetal material was rich in kaempferol-3-O-rutinoside (mean value 2247.09 mg/kg of dry plant), quinic acid (95628.00 mg/kg of dry plant), arginine (mean value of 1.18 mg/kg of dry plant), palmitic acid (284.48 mg/kg) and β-sitosterol (28%). The extracts presented a concentration-dependent antiradical activity (against DPPH, O2•- and LOO), being most effective against NO (EC25 0.20 µg/mL). In addition, the extracts were also acetylcholinesterase inhibitors and antibacterial active, revealing that, besides the plant's good nutritional value, it presents important biological properties as well.

Palavras-chave : acetylcholinesterase inhibition antibacterial activity; antioxidant activity; Capsella bursa-pastoris; metabolic profile.

        · texto em Inglês     · Inglês ( pdf epdf )


Creative Commons License Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons