Abstract

GONCALVES, Lucas D. et al. Contribution for the phytochemical studies of Ageratum fastigiatum. Rev. bras. farmacogn. [online]. 2011, vol.21, n.6, pp. 936-942.  Epub Aug 26, 2011. ISSN 0102-695X.  http://dx.doi.org/10.1590/S0102-695X2011005000151.

Organic extracts from leaves plus branches plus inflorescences of Ageratum fastigiatum (Gardner) R. M. King & H. Rob., Asteraceae, were fractionated through classic chromatography. The steroids stigmasterol, chondrillasterol and campesterol were isolated from hexane extract. The triterpenes lupeol, taraxasterol, α-amyrin, β-amyrin, pseudotaraxasterol, lupeol acetate and α-amyrin acetate were isolated from ethyl acetate extract. Steroids and triterpenes were identified by GC-MS. The coumarin ayapin was isolated from ethanol extract and identified by NMR. Essential oils of the fresh leaves and fresh inflorescences were obtained by hydrodistillation and analyzed for GC-MS. The main components in both essential oils were α-pinene, limonene and germacrene D.

Keywords : aerial parts; Ageratum fastigiatum; Asteraceae; essential oils; Eupatorieae.