Abstract

AZUMA, Cinthia M.; SANTOS, Flávia Cristina S. dos  and  LAGO, João Henrique G.. Flavonoids and fatty acids of Camellia japonica leaves extract. Rev. bras. farmacogn. [online]. 2011, vol.21, n.6, pp. 1159-1162.  Epub July 29, 2011. ISSN 0102-695X.  http://dx.doi.org/10.1590/S0102-695X2011005000128.

The ethanol extract from the leaves of Camellia japonica L., Theaceae, showed antiradical potential in the DPPH test using TLC plates (SiO₂). Aiming the isolation of active compounds, this extract was partitioned between BuOH:H₂O (1:1) and the two obtained phases were also evaluated to detection of antiradical activity. The active BuOH phase was fractionated in Sephadex LH-20 and silica (normal or reverse phase) to afford three aglycone flavonoids (quercetin, kaempferol and apigenin), which have been described in the C. japonica at first time, two glycosilated flavonoids (rutin and quercetrin), and a mixture of saturated fatty acids. The structures of isolated compounds were defined by NMR and GC/MS analyses.

Keywords : antiradical potential; Camellia japonica; fatty acids; flavonoids.