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Revista Brasileira de Farmacognosia
Print version ISSN 0102-695X
PEREIRA, Renato C. and COSTA-LOTUFO, Leticia V.. Bioprospecting for bioactives from seaweeds: potential, obstacles and alternatives . Rev. bras. farmacogn. [online]. 2012, vol.22, n.4, pp.894-905. Epub June 05, 2012. ISSN 0102-695X. http://dx.doi.org/10.1590/S0102-695X2012005000077.
Seaweeds are potential sources of high biotechnological interest due to production of a great diversity of compounds exhibiting a broad spectrum of biological activities. On the other hand, there is an urgent need for management options for a sustainable approach to the use of marine organisms as a source of bioactive compounds. This review discusses the bioprospection for bioactive seaweed compounds as pharmaceuticals and antifouling agents, encompassing their potential and possible obstacles and alternatives. In spite of their potential, research on pharmaceuticals and antifouling agents from seaweeds includes mainly the search for molecules that exhibit these biological activities, but lacks of consideration of fundamental and limiting aspects such as the development of alternatives to sustainable supply. However, for the complete development of pharmaceuticals and antifouling compounds in Brazil, marine bioprospection should be more comprehensive, associating the search for molecules with an analysis of their supply. In this way, it is possible to promote sustainable development and conservation of biodiversity, as well as to assert the economic development of Brazil.
Keywords : seaweeds; marine natural products; bioprospection.