A. dactylomela
|
174 also isolated from Laurencia (Suzuki et al., 1999Suzuki, M., Nakano, S., Takahashi, Y., Abe, T., Masuda, M., 1999. Bisezakyne-A and -B, halogenated C15 acetogenins from a Japanese Laurencia species. Phytochemistry 51, 657-662.) |
Activity in increasing blood levels of pentobarbital in a dose-dependent (Kaul and Kulkarni, 1978Kaul, N.P., Kulkarni, S.K., 1978. New drug metabolism inhibitor of marine origin. J. Pharm. Sci. 67, 1293-1296.) |
A. dactylomela
|
178and 45 |
Antifeedant against Carassius auratus (Manzo et al., 2005Manzo, E., Ciavatta, M.L., Gavagnin, M., Puliti, R., Mollo, E., Guo, Y.W., Mattia, C.A., Mazzarella, L., Cimino, G., 2005. Structure and absolute stereochemistry of novel C15-halogenated acetogenins from the anaspidean mollusc Aplysia dactylomela. Tetrahedron 61, 7456-7460.); toxicity to brine shrimp but inactive against marine bacteria (Takahashi et al., 2002Takahashi, Y., Daitoh, M., Suzuki, M., Abe, T., Masuda, M., 2002. Halogenated metabolites from the new Okinawan red alga Laurencia yonaguniensis. J. Nat. Prod. 65, 395-398.) |
A. dactylomela
|
167 and 179, also isolated from Laurencia sp(Vairappan et al., 2001Vairappan, C.S., Daitoh, M., Suzuki, M., Abe, T., Masuda, M., 2001. Antibacterial halogenated metabolites from the Malaysian Laurencia species. Phytochemistry 58, 291-297.) |
Antibacterial activity against marine bacteria (Vairappan et al, 2001aVairappan, C.S., Daitoh, M., Suzuki, M., Abe, T., Masuda, M., 2001. Antibacterial halogenated metabolites from the Malaysian Laurencia species. Phytochemistry 58, 291-297.,bVairappan, C.S., Suzuki, M., Abe, T., Masuda, M., 2001. Halogenated metabolites with antibacterial activity from the Okinawan Laurencia species. Phytochemistry 58, 517-523.) |
A. fasciata = A. brasiliana
|
56, also isolated from Laurencia sp (Brennan and Erickson, 1982Brennan, M.R., Erickson, K.L., 1982. Austradiol acetate and austradiol diacetate, 4,6-dihydroxy-(+)-selinane derivatives from an Australian Laurencia sp.. J. Org. Chem. 47, 3917-3921.; Norte et al., 1989Norte, M., Fernández, J.J., Cataldo, F., González, G., 1989a. E-dihydrorhodophytin, a C15 acetogenin from the red alga Laurencia pinnatifida. Phytochemistry 28, 647-649.; Vairappan and Tan, 2009Waraszkiewicz, S.M., Sun, H.H., Erickson, K.L., 1976. C15 halogenated compounds from the Hawaiian marine alga Laurencia nidifica. Maneonenes. Tetrahedron Lett. 17, 3021-3024.) |
Antifeedant again st Xiphophorus helleri (Kinnel et al., 1977Kinnel, R.B., Duggan, A.J., Eisner, T., Meinwald, J., 1977. Panacene: an aromatic bromoallene from a sea hare (Aplysia brasiliana). Tetrahedron Lett. 18, 3913-3916.); ant ibacte rial activity against Salmonella enteritidis, Vibrio cholerae, Staphylococcus aureus,E. coli, S. typhi and S. thyphimurium (Vairapp an and Tan, 2009Waraszkiewicz, S.M., Sun, H.H., Erickson, K.L., 1976. C15 halogenated compounds from the Hawaiian marine alga Laurencia nidifica. Maneonenes. Tetrahedron Lett. 17, 3021-3024.) |
A. fasciata= A. brasiliana
|
184 |
Antifeedant activity (Kinnel et al., 1979Kinnel, R.B., Dieter, R.K., Meinwald, J., Van Engen, D., Clardy, J., Eisner, T., Stallard, M.O., Fenical, W., 1979. Brasilenyne and cis-dihydrorhodophytin: antifeedant medium-ring haloethers from a sea hare (Aplysia brasiliana). Proc. Natl. Acad. Sci. U. S. A. 76, 3576-3579.) |
A. kurodai
|
190 |
Inhibitor Na, K-ATPase (Okamoto et al., 2001Okamoto, Y., Nitanda, N., Ojika, M., Sakagami, Y., 2001. Aplysiallene, a new bromoallene as an Na, K-ATPase inhibitor from the sea hare, Aplysia kurodai. Biosci. Biotechnol. Biochem. 65, 474-476.) |
A. parvula
|
189 |
Icht hyotoxic activi ty (Myiamoto et al., 1995Myiamoto, T., Ebisawa, Y., Higuchi, R., 1995. Aplyparvunin, a bioactive acetogenin from the sea hare Aplysia parvula. Tetrahedron Lett. 36, 6073-6074.) |