Bactericidal action against Salmonella typhi.
|
Preclinical study (animals/in vitro) |
Osaki et al., 1994Osaki, Y., Kato, T., Yamamoto, K., Okubo, J., Miyazaki, T., 1994. Antimutagenic and bactericidal substances in the fruit body of a Basidiomycete Agaricus blazei, Jun-17. Yakugaku Zasshi 114, 342-350.
|
Yakugaku Zasshi
|
0.263 |
Extracts of A. blazei and aqueous ethanol, did not exercise antimicrobial activity against the strains tested (S. aureus, B. sabtilis, E. coli). |
Preclinical study (animals/in vitro) |
Zhuqiu and Zhang, 2001Zhuqiu, Y., Zhang, Y., 2001. Study of antibacterial effects of Agaricus blazei. J. Food Sci. 22, 84-87.
|
Journal Food Science
|
2.203 |
Protective effect against S. pneumoniae 6B infection (24 h when administered before or together with the inoculation). No effect on antibiotic pneumococci in vitro. |
Preclinical study (animals/in vitro) |
Bernardshaw et al., 2005Bernardshaw, S., Johnson, E., Hetland, G., 2005. An extract of the mushroom Agaricus blazei Murill administered orally protects against systemic Streptococcus pneumoniae infection in mice. Scand. J. Immunol. 62, 393-398.
|
Scandinavian Journal of Immunology
|
1.739 |
Reduction in bacteremia and increased survival (↓ lethal septicemia) in mice with fecal peritonitis. |
Preclinical study (animals/in vitro) |
Bernardshaw et al., 2006Bernardshaw, S., Hetland, G., Grinde, B., Johnson, E., 2006. An extract of the mushroom Agaricus blazei Murill protects against lethal septicemia in a mouse model for fecal periotonitis. Shock 24, 319-320.
|
Shock
|
3.045 |
The ethanol extract (100%) inhibited the growth of Streptococcus mutans UA159 and Streptococcus sobrinus 6715 using the diffusion method in agar. In tests of MIC and MBC, the three extracts (50%, 75% and 100%) had antimicrobial properties. |
Preclinical study (animals/in vitro) |
Lund et al., 2009Lund, R.G., Del Pino, F.A.B., Serpa, R., Nascimento, J.S., Silva, V.M., Ribeiro, G.A., Rosalen, P.L., 2009. Agaricus brasiliensis against mutans streptococci. Pharm. Biol. 47, 910-915.
|
Pharmaceutical Biology
|
1.241 |
A. blazei extracts obtained from low pressure techniques (using various solvents) as well as by supercritical fluid extraction had a higher antibacterial activity toward Gram positive bacteria (S. aureus and B. cereus). However, the extracts tested against Gram-negative bacteria (E. coli, P. aeruginosa) can be classified as weak inhibitors. |
Preclinical study (animals/in vitro) |
Mazzutti et al., 2012Mazzutti, S., Ferreira, S.R.S., Riehl, C.A.S., Smania, A., Smania, F.A., Martínez, J., 2012. Supercritical fluid extraction of Agaricus brasiliensis: antioxidant and antimicrobial activities. J. Supercrit. Fluids 70, 48-56.
|
The journal of supercritical fluids
|
2.371 |
Ethanol extract of A. blazei showed greater antimicrobial activity against the growth of Listeria monocytogenes when compared to other mushrooms. |
Preclinical study (animals/in vitro) |
Stojkovic et al., 2014Stojkovic, D., Reis, F.S., Barros, L., Glamoclija, J., Ciric, A., Barros, L., van Griensven, L.J., Sokovic, M., Ferreira, I.C., 2014. Cultivated strains of Agaricus bisporus and A. brasiliensis: chemical characterization and evaluation of antioxidant and antimicrobial properties for the final healthy product–natural preservatives in yoghurt. Food Funct. 5, 1602-1612.
|
Food Funct
|
2.791 |
Aqueous extract of A. blazei caused a significant reduction in virulence factors (pyocyanin production, motility) and biofilm formation of Pseudomonas aeruginosa. |
Preclinical study (animals/in vitro) |
Soković et al., 2014Soković, M., Ćirić, A., Glamočlija, J., Nikolić, M., van Griensven, L.J.L.D., 2014. Agaricus blazei hot water extract shows anti quorum sensing activity in the nosocomial human pathogen Pseudomonas aeruginosa. Molecules 19, 4189-4199.
|
Molecules
|
2.416 |