Acta Cirurgica Brasileira
versão On-line ISSN 1678-2674
MANTOVANI, Mario; VIDAL, Benedicto Campos e CONCON FILHO, Admar. Tamponamento das lesões hepáticas transfixantes com colágeno tipo I. Acta Cir. Bras. [online]. 1998, vol.13, n.2 ISSN 1678-2674. http://dx.doi.org/10.1590/S0102-86501998000200003.
Over the past 6 years we have used the Sangenstaken-Blackmore balloon to tamponade transfixing hepatic lesions. To replace this foreign body, we have considered the use of type I collagen, manufactured at Univ. Campinas, which can be molded to the entire wounded area, thus tamponading all surface irregularities. In this way, a complete tamponade may be achieved, and bile loss is prevented. Complete absorption of the material removes the problem of a foreign body. Twenty mongrel dogs received a perforating transfixing lesion in the central region of the liver, similar to that caused by a firearm bullet. Into the wounded tunnel type I collagen was introduced. Evaluations were made in the 4th, 7th, 15th and 30th day after the intervention, when animals were sacrificed. Polarizing microscope evaluation induced a homogeneous scar formation, with early, organized hepatic regeneration evident from the 7th day onward. It is therefore believed that the use of type I collagen is an effective and safe method to be used in this type of hepatic wounds.
Palavras-chave : Trauma; Hepatic trauma; Type I collagen; Hepatic regeneration.