SciELO - Scientific Electronic Library Online

 
vol.13 número2Estudo clínico e anatomopatológico da cicatrização cutânea no gato doméstico: utilização do laser de baixa potência GaAs (904 nm)Estudo comparativo do fechamento da incisão mediana abdominal por planos e com o uso de pontos subtotais e tela de poliglactina 910, em ratos índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Artigo

Indicadores

Links relacionados

  • Não possue artigos similaresSimilares em SciELO

Compartilhar


Acta Cirurgica Brasileira

versão On-line ISSN 1678-2674

Resumo

VIEIRA, Antonio Mauro; FAGUNDES, Djalma José; BAZANO, Félix Carlos Ocáriz  e  RAMOS, Eduardo Chibeni Fernandes. Efeitos analgésico e hipnótico das associações do sufentanil com o tiopental e com o propofol, em ratos. Acta Cir. Bras. [online]. 1998, vol.13, n.2 ISSN 1678-2674.  http://dx.doi.org/10.1590/S0102-86501998000200005.

The aim of this study was to evaluate the interactions of the analgesic action of sufentanil with the hypnotic action of thiopental and propofol, in 60 male rats distributed in two groups of 30 and submitted to different doses of sufentanil and propofol, to determine the analgesic (AMD) and hypnotic medium doses (HMD). The AMD of sufentanil was the analgesic dose and HMD of thiopental and propofol was the dose to obtain hypnosis, this is, the lost of righting reflex. There was a prolonged hypnotic action when thiopental with sufentanil and propofol with sufentanil were used together. The analgesic action of sufentanil-thiopental association has a significant increase, and sufentanil-propofol association showed no significant difference when compared to sufentanil alone. The sufentanil-thiopental association had more analgesic and hypnotic action when compared to sufentanil-propofol association. When was compared the concomitant presence of analgesy and hypnosis, the sufentanil-thiopental association had a longer lasting.

Palavras-chave : Interaction drugs; Propofol; Rats; Sufentanil; Thiopental.

        · resumo em Português     · texto em Português