Acta Cirurgica Brasileira
On-line version ISSN 1678-2674
RAMOS, ECF et al. A study about bacterial transmigration in experimental Appendicitis in rabbits. Acta Cir. Bras. [online]. 2000, vol.15, suppl.1, pp. 24-27. ISSN 1678-2674. http://dx.doi.org/10.1590/S0102-86502000000500007.
The present study aims to evaluate the occurrence of the bacterial transmigration in induced ezxperimental appendicitis in rabbitis through complete oclusion of the vermiform appendix. 24 New Zealand white rabbits with a body weight ranging from 2500 to 3000 grams were used. They were divided into 2 groups. The animals from group I were submitted to a median laparotomy and fragments from the spleen, left kidney, right lung, abdominal limphonode, light content from the vermiform appendix and blood from the portal vein were withdrawn for culture. The animals from group 2 were submitted to median laparotomy and complete occlusion of the vermiform appendix in order to induce appendicitis and, after 24 hours, material was collected following the steps of group 1. It was not observed an increase in bacteria in the samples analysed in the Control Group Group 1). The increase of Escherichia coli was observed in all the animals from the Experiment Group (Group 2). The bacterial transmigration occured after 24-hour observation in rabbits with experimental appendicitis.
Keywords : Experimental appendicitis; Bacterial transmigration; Rabbits.