Revista Paulista de Pediatria
Print version ISSN 0103-0582
GOMES, Patrícia Boechat et al. Polietilenoglicol na constipação intestinal crônica funcional em criançasPolyethylene glycol in the treatment of chronic functional constipation in children. Rev. paul. pediatr. [online]. 2011, vol.29, n.2, pp. 245-250. ISSN 0103-0582. http://dx.doi.org/10.1590/S0103-05822011000200017.
OBJECTIVE: To review the literature about the use of the polyethylene glycol in the treatment of chronic functional constipation in children. DATA SOURCE: Articles published between 1998 and 2009 were selected from Medline and SciELO databases. Relevant articles concerning constipation, the use of polyethylene glycol in adults, the recent NASPGHAN guideline and the ROMA III criteria were also included. DATA SYNTHESIS: The treatment of functional constipa-tion in children is composed of several stages, among which is the long-term use of laxative drugs. The therapeutic options are limited and they carry problems related to long-term use, especially due to the adverse effects and child's low adherence to the treatment. Polyethylene glycol is an odorless, tasteless and minimally absorbed osmotic agent, available in 3350 and 4000 molecular weights, with or without electrolytes. Good results have been reported in controlled and randomized studies regarding the improve-ment of symptoms of constipation. It is considered safe, without significant side effects. CONCLUSIONS: Polyethylene glycol is superior to other osmotic agents as far as taste and children's acceptance are concerned. Low daily doses are safe and effective. It is a good treatment option for chronic functional constipation in children.
Keywords : child; constipation; polyethylene glycol.