Revista Paulista de Pediatria
Print version ISSN 0103-0582
ZANONI, Lourdes Zélia et al. Usage of L-carnitine as adjuvant in the treatment of dilated cardiomyopathy in a child with Aids. Rev. paul. pediatr. [online]. 2011, vol.29, n.2, pp.289-293. ISSN 0103-0582. http://dx.doi.org/10.1590/S0103-05822011000200022.
OBJECTIVE: To present the cardiovascular response to L-carnitine of a patient with congestive heart failure caused by dilated cardiomyopathy and human immunodeficiency virus. CASE DESCRIPTION: Child with a clinical history of severe congestive heart failure due to dilated cardiomyopathy caused by acquired immunodeficiency syndrome. The treatment for the symptoms resulted in a poor clinical response. In order to improve the energetic performance/metabolism of cardiomyocytes, therapy with L-carnitine was established. There was significant clinical improvement of the cardiac performance of the patient, even before starting the treatment with antiretroviral drugs. COMMENTS: L-carnitine is a compound that facilitates the transport of long-chain fatty acids into the mitochondria. In this case the administration of L-carnitine appears to be clinically and biochemical justified.
Keywords : L-carnitine; cardiomyopathy, dilated; acquired immunodeficiency syndrome; child.