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vol.37 número3INSERÇÃO DO PAI NOS CUIDADOS AO FILHO PREMATURO HOSPITALIZADO: PERCEPÇÃO DA EQUIPE MULTIPROFISSIONALDERMATOSES NO PERÍODO NEONATAL PRECOCE: ASSOCIAÇÃO COM VARIÁVEIS NEONATAIS, OBSTÉTRICAS E DEMOGRÁFICAS índice de autoresíndice de assuntospesquisa de artigos
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Revista Paulista de Pediatria

versão impressa ISSN 0103-0582versão On-line ISSN 1984-0462

Resumo

SILVA, Alyne Batista da et al. INTRAUTERINE GROWTH AND THE VITAMIN E STATUS OF FULL-TERM AND PRETERM NEWBORNS. Rev. paul. pediatr. [online]. 2019, vol.37, n.3, pp.291-296.  Epub 09-Maio-2019. ISSN 0103-0582.  https://doi.org/10.1590/1984-0462/;2019;37;3;00003.

Objective:

To determine the concentration of alpha-tocopherol in umbilical cord serum of full-term and preterm newborns, in order to assess the nutritional status of both groups in relation to the vitamin and its possible correlation with intrauterine growth.

Methods:

A cross-sectional observational study conducted with 140 newborns, of which 64 were preterm and 76 were full-term. They did not have any malformations, they came from healthy mothers, who were nonsmokers, and delivered a single baby. Intrauterine growth was evaluated by weight-to-gestational age at birth, using Intergrowth-21st. Thealpha-tocopherol levels of umbilical cord serum were analyzed by High Performance Liquid Chromatography.

Results:

The mean concentration of alpha-tocopherol in umbilical cord serum for preterm and full-term infants was 263.3±129.5 and 247.0±147.6 µg/dL (p=0.494). In the preterm group, 23% were small for gestational age, whereas in the full-term group, this percentage was only 7% (p=0.017). Low levels of vitamin E were found in 95.3% of preterm infants and 92.1% of full-term infants. There was no correlation between alpha-tocopherol levels and weight to gestational age Z score (p=0.951).

Conclusions:

No association was found between alpha-tocopherol levels and weight to gestational age at birth. Intrauterine growth restriction was more frequent in preterm infants and most infants had low levels of vitamin E at the time of delivery.

Palavras-chave : Alpha-Tocopherol;Premature infants; Nutritional status;Umbilical cord.

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