E199. Wright JE. Appendicitis in childhood: Reduction in wound infection with preoperative antibiotics. Aust N Z J Surg. 1982;52:127-9.
|
Wright (1982)/England/Royal Newcastle Hospital |
Cohort (n=118) |
E21313. Schmitt F, Clermidi P, Dorsi M, Cocquerelle V, Gomes CF, Becmeur F. Bacterial studies of complicated appendicitis over a 20-year period and their impact on empirical antibiotic treatment. J Pediatr Surg. 2012;47:2055-62.
|
Schmitt et al. (2012)/France/Strasbourg University Hospital |
Retrospective (n=176) |
E31717. Guillet-Caruba C, Cheikhelard A, Guillet M, Bille E, Descamps P, Yin L, et al. Bacteriologic epidemiology and empirical treatment of pediatric complicated appendicitis. Diagn Microbiol Infect Dis. 2011;69:376-81.
|
Guillet Caruba et al. (2011)/France/Necker-Enfants Malades Hospital |
Cohort (n=93) |
E41414. Yu TC, Hamill JK, Evans SM, Price NR, Morreau PN, Upadhyay VA, et al. Duration of postoperative intravenous antibiotics childhood complicated appendicitis: a propensity score-matched comparison study. Eur J Pediatr Surg. 2014;24:341-9.
|
Yu et at. (2014)/New Zealand/Starship Children’s Hospital |
Cohort (n=47) |
E51515. Loux TJ, Falk GA, Burnweit CA, Ramos C, Knight C, Malvezzi L. Early transition to oral antibiotics for treatment of perforated appendicitis in pediatric patients: Confirmation of the safety and efficacy of a growing national trend. J Pediatr Surg. 2016;51:903-7.
|
Loux et al. (2016)/United State of America/Miami Children’s Hospital |
Coohort(n=115) |
E61818. Chan KW, Lee KH, Mou JW, Cheung ST, Sihoe JD, Tam YH. Evidence-based adjustment of antibiotic in pediatric complicated appendicitis in the era of antibiotic resistance. Pediatr Surg Int. 2010;26:157-60.
|
Chan et al. (2010)/China/Prince of Wales Hospital Hong Kong |
Observational retrospective (n=250) |
E71010. Kronmam MP, Oron AP, Ross RK, Hersh AL, Newland JG, Golding A, et al. Extended-versus narrower-spectrum antibiotics for appendicitis. Pediatrics. 2016;138:1-9.
|
Kronman et al. (2016)/United State of America/ multicenter (23 independent children’s hospitals) |
Retrospective cohort (n=24.984) |
E81111. Kizilcan F, Tanyel FC, Büyükpamukçu N, Hiçsönmez. The necessity of prophylactic antibiotics in uncomplicated appendicitis during childhood. J Pediatr Surg. 1992;27:586-8.
|
Kizilcan et al. (1992)/Turkey/Hacettepe Children’s Hospital |
Randomized clinical trial (n=100) |
E91919. Shandling B, Ein SH, Simpson JS, Stephens CA, Bandi SK. Perforating appendicitis and antibiotics. J Pediatr Surg. 1974;9:79-83.
|
Shandling et al. (1974)/Canada/Hospital for Sick Children |
Retrospective(n=550) |
E102020. Foster MC, Morris DL, Legan C, Kapila L, Slack RC. Perioperative prophylaxis with sulbactam and ampicillin compared with metronidazole and cefotaxime in the prevention of wound infection in children undergoing appendectomy. J Pediatr Surg. 1987;22:869-72.
|
Foster et al. (1987)/England/University Hospital |
Randomized clinical trial (n=100) |
E112121. van Wijck K, Jong JR, van Heurn LW, van der Zee DC. Prolonged antibiotic treatment does not prevent intra-abdominal abscesses in perforated appendicitis. World J Surg. 2010;34:3049-53.
|
Wijck et al. (2010)/Holanda/two teaching hospitals |
Observational retrospective (n=49) |
E121212. Söderquist-Elinder C, Hirsch K, Bergdahl S, Rutqvist J, Frenckner B. Prophylactic antibiotics in uncomplicated appendicitis during childhood - a prospective randomized study. Eur J Pediatr Surg. 1995;5:282-5.
|
Söderquist Elinder et al. (1995)/France/St. Goran’s Children’s Hospital |
Randomized clinical trial (n=544) |
E132222. David IB, Buck JR, Filler RM. Rational use of antibiotics for perforated appendicitis in childhood. J Pediatr Surg. 1982;17:494-500.
|
David et al. (1982)/Canada/Hospital for Sick Children |
Retrospective (n=300) |
E142323. Rice HE, Brown RL, Gollin G, Caty MG, Gilbert J, Skinner MA, et al. Results of a pilot trial comparing prolonged intravenous/oral antibiotics for children with perforated appendicitis. Arch Surg. 2001;136:1391-5.
|
Rice et al. (2001)/United States of America/multicenter (five centers) |
Randomized clinical trial (n=26) |
E151616. St Peter SD, Tsao K, Spilde TL, Holcamb GW, Sharp SW, Murphy JP, et al. Single daily dosing ceftriaxone and metronidazole vs standard triple antibiotic regimen for perforated appendicitis in children: a prospective randomized trial. J Pediatr Surg. 2008;43:981-5.
|
St Peter et al. (2008)/United States of America/The Children’s Mercy Hospital |
Randomized clinical trial (n=100) |
E162424. Ein SH, Sandler A. Wound infection prophylaxis in pediatric acute appendicitis: a 26-year prospective study. J Pediatr Surg. 2006;41:538-41.
|
Ein et al. (2006)/Canada/Hospital for Sick Children |
Cohort (n=453) |
E172525. Fallon SC, Hassan SF, Larimer EL, Rodriguez JR, Brandt ML, Wesson DE, et al. Modification of an evidence-based protocol for advanced appendicitis in children. J Surg Res. 2013;185:273-7.
|
Fallon et al. (2011)/United States of America /Texas Children’s Hospital |
Cohort(n=50) |
E182626. Obinwa O, Casidy M, Flynn J. The microbiology of bacterial peritonitis due to appendicitis in children. Ir J Med Sci. 2014;183:585-91.
|
Obinwa et al. (2014)/Ireland/Portiuncula Hospital |
Retrospective(n=69) |
E192727. Marchildon MB, Dudgeon DL. Perforated appendicitis: current experience in a children's hospital. Ann Surg. 1977;185:84-7.
|
Marchildon et al. (1977)/United States of America /Children’s Hospital of Los Angeles |
Retrospective(n=89) |
E202828. Dalgic N, Karadag CA, Bayraktar B, Sancar M, Kara O, Pelit S, et al. Ertapenem versus standard triple antibiotic therapy for the treatment of perforated appendicitis in pediatric patients: a prospective randomized trial. Eur J Pediatr Surg. 2014;24:410-8.
|
Dalgic et al. (2014)/Turkey/Sisli Etfal Training and Research Hospital |
Randomized clinical trial (n=107) |
E212929. Uhari M, Seppänen J, Heikkinen E. Imipenem-cilastatina vs tobramycin and metronidazole for appendicitis-related infections. Pediatr Infect Dis J. 1992;11:445-50.
|
Uhari et al. (1992)/Finland/Department of Pediatrics, University of Oulu |
Randomized clinical trial (n=218) |
E223030. Ein SH, Nasr A, Ein A. Open appendectomy for pediatric ruptured appendicitis: a historical clinical review of the prophylaxis of wound infection and postoperative intra-abdominal abscess. Can J Surg. 2013;56:E7-12.
|
Ein et al. (2013)/Canada/Hospital for Sick Children |
Epidemiological - historical series (n=496) |
E233131. Acker SN, Hurst AL, Bensard DD, Schubert A, Dewberry L, Gonzales D, et al. Pediatric appendicitis and need for antibiotics at time of discharge: Does route of administration matter? J Pediatr Surg. 2016;51:1170-3.
|
Acken et at. (2016)/United States of America/Children’s Hospital Colorado |
Epidemiological - historical series (n=325) |
E243232. Desai AA, Alemayehu H, Holcomb GW, St Peter SD. Safety of a new protocol decreasing antibiotic utilization after laparoscopic appendectomy for perforated appendicitis in children: a prospective observational study. J Pediatr Surg. 2015;50:912-4.
|
Desai et al. (2015)/United States of America/ Children’s Mercy Hospital and Clinics |
Cohort (n=540) |