Acessibilidade / Reportar erro

In vivo and in vitro studies of a cetylamine fluoride mouthrinse: evaluation of a device used for in vitro experiments

Estudos in vivo e in vitro de enxaguatório bucal contendo cetilamino fluoreto: validação de dispositivo usado nos experimentos in vitro

A mouthrinse containing cetylamine fluoride (230 ppm in fluoride) was prepared for in vitro studies of fluoride clearance and adsorption by enamel and/or hydroxyapatite using a device that simulates the oral cavity. In vivo studies of fluoride clearance from this mouthrinse were conducted and compared with other fluoride sources. The amount of fluoride adsorbed to tooth blocks or powdered hydroxyapatite, both treated with this cetylamine fluoride mouthrinse once or twice a day, was determined. The results of these studies showed that it is possible to prepare a mouthrinse with cetylamine fluoride for alternative use by patients for the prevention and therapy of dental caries.

Fluorides; Monthwashes; Clearance; Adsorption


Universidade de São Paulo Avenida Lineu Prestes, 2227 - Caixa Postal 8216, Cidade Universitária Armando de Salles Oliveira, 05508-900 São Paulo SP - Brazil, Tel.: (55 11) 3091-7861, Fax: (55 11) 3091-7413 - São Paulo - SP - Brazil
E-mail: pob@edu.usp.br