A21818 Goulart IMB, Souza DOB, Marques CR, et al. Risk and Protective Factors for Leprosy Development Determined by Epidemiological Surveillance of Household Contacts. Clin Vaccine Immunol. [internet]. 2008 [acesso em 2018 jun 14]; 15(1):101-105. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223848/. https://www.ncbi.nlm.nih.gov/pmc/article...
|
Brazil 2008 |
Case-control |
To characterize important risk factors associated with the incidence of leprosy in household contacts |
The contacts of patients with lepromatous leprosy were 3.8 times more likely to develop leprosy. All unfavorable combinations of the two and three tests generated significant risk values ranging from 5.76 to 24.47, with the highest risk given by the combination of no BCG scar, negative Mitsuda test and positive ML-Flow test. The positive ML-Flow test indicated a six times higher relative risk for the occurrence of the disease. |
4 |
A41919 Dessunti EM, Soubhia Z, Alves E, et al. Hanseníase: o controle dos contatos no município de Londrina-PR em um período de dez anos. Rev. bras. enferm. [internet]. 2008 [acesso em 2018 jun 15]; 61(spe):689-693. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S003471672008000700006&lng=en. http://www.scielo.br/scielo.php?script=s...
|
Brazil 2008 |
Descriptive, retrospective, quantitative |
To analyze variables related to the intra-domiciliary contacts of patients with leprosy treated in the municipality of Londrina in a period of ten years |
There were 3,394 contacts registered, with an average of 3.2 per case. 71.5% aged up to 40 years, children (40.6%) and spouse (17.8%). Of the 1,731 contacts examined (51.0%), 183 had any signs of leprosy: 16 confirmed cases. 51.6% were exposed to multibacillary forms and 10.1% evidenced two doses of BCG. |
6 |
A62020 Durães SMB, Guedes LS, Cunha MD, et al. Estudo epidemiológico de 107 focos familiares de hanseníase no município de Duque de Caxias - Rio de Janeiro, Brasil. An. bras. dermatol. [internet]. 2010 [acesso em 2018 jun 15]; 85(3):339-345. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S036505962010000300007&lng=en. http://www.scielo.br/scielo.php?script=s...
|
Brazil 2010 |
Analytical, observational, cross-sectional, quantitative |
To analyze the clinical-epidemiological profile of co-prevalent cases and to identify risk factors for illness among leprosy contacts |
The controlled analysis of the type of contact and degree of relatedness variables revealed that home contact and first-degree relatedness are independently associated with a higher probability of becoming ill. |
6 |
A102121 Sarno EN, Duarte NC, Vendas AM, et al. Exposição à hanseníase, infecção e doença: um estudo de vigi lância de 25 anos dos contatos de pacientes com hanseníase. Mem. Inst. Oswaldo Cruz [internet]. 2012 [acesso em 2018 jun 15]; 107(8):1054-1059. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000800015&lng=en. http://www.scielo.br/scielo.php?script=s...
|
Brazil 2012 |
Analytical, observational, retrospective, quantitative |
To review data of the cohort of contacts over the past 25 years on the major risk factors leading to the infectious phase of the disease, estimate the incidence rates of leprosy in the cohort and to characterize the risk factors for the disease among contacts under surveillance |
The factors associated with the acquisition of the disease were: not receiving the BCG vaccine, a negative reaction of Mitsuda and contact with patients with multibacillary clinical form. The factors associated with the infection defined as a seropositivity for IgM anti-phenolic-glycolipid-1: young age (<20 years old), low measured Mitsuda reaction (<5 mm) and contact with an indexed patient with high bacilloscopic index. |
6 |
A142222 Lima CSO, Galvão MHR, Brito FM, et al. Leprosy: surveillance of contacts. Rev. enferm. UFPE [internet]. 2014 [acesso em 2018 jun 15]; 8(5):1136-41. Disponível em: https://periodicos.ufpe.br/revistas/revistaenfermagem/article/view/9791. https://periodicos.ufpe.br/revistas/revi...
|
Brazil 2014 |
Descriptive, retrospective, quantitative |
To characterize the communicators of leprosy patients in a public hospital |
It was observed influence of the consanguinity factor in the transmission, besides deficiency in the dermatoneurological evaluation of the communicants people. |
6 |
A172323 Lobato DC, Neves DCO, Xavier MB. Avaliação das ações da vigilância de contatos domiciliares de pacientes com hanseníase no Município de Igarapé-Açu, Estado do Pará, Brasil. Rev. Pan-Amazônica Saúde [internet]. 2016 [acesso em 2018 jun 15]; 7(1):45-53. Disponível em:http://scielo.iec.gov.br/scielo.php?script=sci_arttext&pid=S2176-62232016000100006&lng=pt. http://scielo.iec.gov.br/scielo.php?scri...
|
Brazil 2016 |
Descriptive, retrospective, quantitative |
To evaluate the actions of the surveillance of household contacts of patients with leprosy in the Municipality of Igarapé-Açu, State of Pará, Brazil, from 2004 to 2008 |
Of the 133 contacts identified, 52.63% were male; 42.10%, incomplete elementary school; 42.85%, singles; 55.63%, unemployed; 60.15%, family income less than 1 minimum wage; and 67.67%, a BCG scar. The rate of not assessed contacts was 84 (63.16%), and of these, 56 (66.70%) were contacts of multibacillary cases. |
6 |
A182424 Romero-Montoya M, Beltran-Alzate JC, Cardona-Castro N. Evaluation and monitoring of mycobacterium leprae transmission in household contacts of patients with hansen's disease in Colombia. Plos negl. trop. dis. [internet]. 2017 [acesso em 2018 jun 15]; 11(1):e0005325. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289623/. https://www.ncbi.nlm.nih.gov/pmc/article...
|
Colombia 2017 |
Analytical, observational, prospective, quantitative |
To evaluate the transmission of leprosy in family groups of leprosy patients from four Colombian departments: Antioquia, Bolivar, Cordoba and Sucre |
159 Family Groups (FG) formed by 543 household contacts (HHCs) were evaluated. Twenty-two (4.1%) of the 543 HHCs had positive anti-PGL-I IgM antibody titers, indicating infection. The genotype of the two strains (HHCs and index case) was in agreement with 9 markers, showing individuals infected by the same strain, indicating family transmission. |
6 |