A new natural quaternary alkaloid, Nb-methylvoachalotine (1), was obtained from the root bark of Tabernaemontana laeta together with three dimeric indole alkaloids, conodurine (2), voacamine (3) and tabernamine (4), and the monomeric indole alkaloids 19S-heyneanine (5), coronaridine (6) and voacangine (7). The known triterpenes alpha-amyrin acetate, beta-amyrin acetate, lupeol acetate and taraxasterol acetate and the phytosterol beta-sitosterol and its 3-O-beta-D-glucoside were also identified. The structures of the compounds were elucidated based on spectroscopic studies.
Tabernaemontana laeta; Apocynaceae; indole-alkaloids; triterpenes
