Resumo

CHAVES, Mariana H.; LAGO, João Henrique G.  e  ROQUE, Nídia F.. Macrocarpane, a new sesquiterpene skeleton from the leaves of Porcelia macrocarpa. J. Braz. Chem. Soc. [online]. 2003, vol.14, n.1, pp. 16-19. ISSN 0103-5053.  http://dx.doi.org/10.1590/S0103-50532003000100004.

The volatile oil and the hexane extract from the leaves of Porcelia macrocarpa (Warm.) R.E. Fries, Annonaceae, were submitted to chromatographic separations. Nine sesquiterpenes (a-cubebene, a-copaene, germacrene-D, bicyclogermacrene, g-cadinene, d-cadinene, spathulenol, globulol and cis-cubenol) and one diterpene (phytol) were identified in the volatile oil (83.1 % in weight). Two sesquiterpenes (spathulenol and macrocarp-11(15)-en-8-ol), the latter with a novel skeleton, one diterpene (phytol) and two steroids (sistosta-5,25-dien-3b-ol and sitosta-5,22,25-trien-3b-ol) were isolated from the hexane extract. These compounds were characterized by ¹H and ¹³C NMR spectroscopy, including bidimensional analysis and mass spectrometry.

Palavras-chave : macrocarpane; spathulenol; steroids; sesquiterpenes; Porcelia macrocarpa.