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Thermodynamic study of the solubility of some sulfonamides in cyclohexane

The thermodynamic functions Gibbs energy, enthalpy and entropy of solution in cyclohexane, were evaluated from solubility data for a group of sulfonamides over the temperature range from 20.0 to 40.0 °C. The excess Gibbs energy and the activity coefficients of the solutes were also determined. The results are discussed in terms of solute-solvent interactions.

sulfonamides; solubility; solution thermodynamics; activity coefficient; cyclohexane


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