Journal of the Brazilian Chemical Society
On-line version ISSN 1678-4790
ZAMUNER, M. Lucília M. et al. Lanostane triterpenes from the fungus Pisolithus tinctorius. J. Braz. Chem. Soc. [online]. 2005, vol.16, n.4, pp. 863-867. ISSN 1678-4790. http://dx.doi.org/10.1590/S0103-50532005000500028.
A new triterpene, 3b,22x,23x-trihydroxy-24-methyllanosta-8,24(28)-diene-31-al 22-acetate, named pisosteral, and four known lanostane triterpenes derivatives, 3b,22x,23x-trihydroxy-24-methyllanosta-8,24(28)-diene 22-acetate (pisosterol), 3a,22x,23x-trihydroxy-24-methyllanosta-8,24(28)-diene 22-acetate (3-epi-pisosterol), 3b,22x,23x-trihydroxy-24-methyllanosta-8,24(28)-diene 23-acetate and 3b,22x,23x-trihydroxy-24-ethyllanosta-8,24(28)-diene 22-acetate, were isolated from fruiting bodies of Pisolithus tinctorius, collected in an Eucalyptus plantation. From cultivation of a strain of P. tinctorius isolated from Pinus taeda, four known triterpenes lanostane derivatives, 3b,22x-dihydroxy-24-methyllanosta-8,24(28)-diene, 3b,22x-dihydroxy-24-ethyllanosta-8,24(28)-diene, 3b-hydroxylanosta-8,24-diene (lanosterol) and 3b-hydroxylanosta-7(8),9,24-triene (agnosterol), were isolated. These compounds were identified on the basis of chemical and physical methods, mainly mass spectrometry and 1D and 2D nuclear magnetic resonance.
Keywords : triterpene; lanostane; Pisolithus tinctorius; fungus; basidiomycete.