Journal of the Brazilian Chemical Society
On-line version ISSN 1678-4790
PEREZ, Herminia I. et al. Nitrile hydratase activity of Nocardia corallina B-276. J. Braz. Chem. Soc. [online]. 2005, vol.16, n.6a, pp. 1150-1153. ISSN 1678-4790. http://dx.doi.org/10.1590/S0103-50532005000700010.
The nitrile hydratase activity of Nocardia corallina B-276 is described, and the only detected product during the biocatalyzed hydrolysis of selected nitriles was the corresponding amide. The best results were obtained using a suspension of cells in a phosphate buffer (pH= 7.0), with conversion percentages ranging from 31% to > 99%.
Keywords : nitrile hydratase; biotransformation; nitriles; amides; Nocardia corallina.