Two new clerodane diterpenes, crotobrasilin A and crotobrasilin B, were isolated in addition to four known 3-methoxyflavones: casticin, penduletin, chrysosplenol-D and artemetin from leaves and stems of Croton brasiliensis. The structural elucidation of these compounds was made on the basis of spectroscopic data analyses, especially NMR, including 2D techniques (COSY, HMQC, HMBC and NOESY).
Croton brasiliensis; clerodane diterpenes; 3-methoxyflavones
