A series of beta-amino esters alpha,beta-unsaturated ketones and esters 4a-h and 6a-d derived from alpha-amino acids have been prepared starting from alpha-amino esters hydrochorides 2a-d with 1,3- dicarbonyl compounds 3a,b and 5 in presence of triethylamine. These compounds have been prepared under domestic microwave oven, under solvent free condition with and without solid support (K-10 or KSF).
alpha-amino acids; solid support; microwave; alpha-amino esters