Journal of the Brazilian Chemical Society
versão impressa ISSN 0103-5053
MANJARREZ, Norberto et al. Biotransformation of (S)-cis-verbenol with Nocardia corallina B-276. J. Braz. Chem. Soc. [online]. 2007, vol.18, n.4, pp. 709-713. ISSN 0103-5053. http://dx.doi.org/10.1590/S0103-50532007000400007.
The biotransformation of (S)-cis-verbenol with Nocardia corallina was investigated using two methods: Suspension of cells in a phosphate buffer (pH 7) with various substrate:cells ratios; and bioreactor of 3-L with cells in the culture media. Both gave (1S)-(-)-verbenone with excellent yields ranging from >99 to 98%, at scale of 0.7 and 7 mmol respectively.
Palavras-chave : biocatalysis; (1S)-(-)-verbenone; oxidations; Nocardia corallina.