Journal of the Brazilian Chemical Society
versión impresa ISSN 0103-5053
versión On-line ISSN 1678-4790
TAKEARA, Renata et al. Sample optimization for rapid identification of nucleosides and bases from ascidian extracts using ESI-MS/MS. J. Braz. Chem. Soc. [online]. 2007, vol.18, n.5, pp.1054-1060. ISSN 0103-5053. http://dx.doi.org/10.1590/S0103-50532007000500027.
Electrospray ionization tandem mass spectrometry (ESI-MS/MS) method was developed for identification of nucleosides and bases in extracts of ascidians. For this study a systematic sample preparation associated with the fragmentation pattern of a series of nucleosides and bases using ESI-MS/MS was done. These approaches constitute powerful analytical tools for rapid screening and structural assignment of nucleosides and bases in ascidian extracts.
Palabras clave : natural products; ESI-MS/MS; ascidian; nucleosides; glycosylamines.