Journal of the Brazilian Chemical Society
versão impressa ISSN 0103-5053
SILVA, Viviane C. da; BOLZANI, Vanderlan da S.; YOUNG, Maria C. M. e LOPES, Márcia N.. A new antifungal phenolic glycoside derivative, iridoids and lignans from Alibertia sessilis (vell.) k. schum. (Rubiaceae). J. Braz. Chem. Soc. [online]. 2007, vol.18, n.7, pp. 1405-1409. ISSN 0103-5053. http://dx.doi.org/10.1590/S0103-50532007000700017.
A new antifungal phenolic glycoside, 3,4,5-trimethoxyphenyl-1-O-b-D-(5-O-syringoyl)apiofuranosyl-(1®6)-b-D-glucopyranoside (1), together with four known iridoids, geniposidic acid (2), geniposide (3), 6a-hydroxygeniposide (4) and 6b-hydroxygeniposide (5); two lignans, (+)-lyoniresinol-3a-O-b-D-glucopyranoside (6), (-)-lyoniresinol-3a-O-b-D-glucopyranoside (7); and two phenolic acids, chlorogenic (8) and salicylic acids (9) and D-manitol (10), were isolated from the ethanolic extract of the stems of Alibertia sessilis. Structures of 1 and of the known compounds were determined by spectroscopic analysis. All compounds isolated were evaluated for their antifungal activities against two phytopathogenic fungi strains Cladosporium cladosporioides and C. sphaerospermum by direct bioautography.
Palavras-chave : Rubiaceae; Alibertia sessilis; phenolics; iridoids; antifungal.