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Clausenain B, a phenylalanine-rich cyclic octapeptide from Clausena anisum-olens

A new cyclic octapeptide, named clausenain B, was isolated by a multi-step chromatography procedure from Clausena anisum-olens. Its structure was established as cyclo(-Phe¹-Ser-Leu¹-Phe²-Phe4-Gly-Leu²-Phe³-) (1) based on extensive spectroscopic studies and chemical evidence. Clausenain B (1) is a phenylalanine-rich cyclic octapeptide.

Rutaceae; Clausena anisum-olens; cyclic octapeptide; clausenain B


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