Resumen

NEVES FILHO, Ricardo A. W.; BEZERRA, Natércia M. M.; GUEDES, José M.  y  SRIVASTAVA, Rajendra M.. An easy synthesis of 3,5-disubstituted 1,2,4-oxadiazoles from carboxylic acids and arylamidoximes mediated by ethyl chloroformate. J. Braz. Chem. Soc. [online]. 2009, vol.20, n.7, pp. 1365-1369. ISSN 0103-5053.  http://dx.doi.org/10.1590/S0103-50532009000700023.

An efficient, clean and easy high-yielding synthesis of 3,5-disubstituted 1,2,4-oxadiazoles starting from mixed anhydrides (generated from carboxylic acids and ethyl chloroformate) and arylamidoximes is described.

Palabras llave : carboxylic acids; arylamidoximes; 1,2,4-oxadiazoles; ¹H and ¹³C NMR spectra.