Abstract

CASARANO, Romeu; PETRI, Denise F. S.; JAFFE, Michael  and  CATALANI, Luiz H.. Synthesis and structural characterization of block and random low molecular weight copolymers composed of L-lactic acid and isosorbide succinate moieties. J. Braz. Chem. Soc. [online]. 2009, vol.20, n.8, pp. 1414-1424. ISSN 0103-5053.  http://dx.doi.org/10.1590/S0103-50532009000800005.

Isosorbide succinate moieties were incorporated into poly(L-lactide) (PLLA) backbone in order to obtain a new class of biodegradable polymer with enhanced properties. This paper describes the synthesis and characterization of four types of low molecular weight copolymers. Copolymer I was obtained from monomer mixtures of L-lactide, isosorbide, and succinic anhydride; II from oligo(L-lactide) (PLLA), isosorbide, and succinic anhydride; III from oligo(isosorbide succinate) (PIS) and L-lactide; and IV from transesterification reactions between PLLA and PIS. MALDI-TOFMS and ¹³C-NMR analyses gave evidence that co-oligomerization was successfully attained in all cases. The data suggested that the product I is a random co-oligomer and the products II-IV are block co-oligomers.

Keywords : isosorbide; PLLA; PIS; copolymers; MALDI-TOF.