Abstract

RODRIGUES, Francisco E. A. et al. Diterpene and other constituents from Stemodia maritima (Scrophulariaceae). J. Braz. Chem. Soc. [online]. 2010, vol.21, n.8, pp. 1581-1586. ISSN 0103-5053.  http://dx.doi.org/10.1590/S0103-50532010000800025.

A new diterpene, (5S*,8S*,9R*,10S*)-11β,12β-epoxy-9α-hydroxy-19(4→3) abeo-abieta-3,13-diene-19,18-olide, together with the known compounds stemodin, D-mannitol, betulinic acid, a mixture of 3β-O-β-D-glucopyranosyl-β-sitosterol and 3β-O-β-D-glucopyranosylstigmasterol and 5,7,4'-trihydroxy-3,8,3'-trimethoxyflavone were isolated from the leaves and stems of Stemodia maritima. Structural elucidation of all compounds was based on interpretation of spectral data, mainly NMR (1D and 2D) and MS, including comparison with values described in the literature.

Keywords : Stemodia maritima; Scrophulariaceae; diterpenes; steroids; flavonoids.