Revista Brasileira de Terapia Intensiva
versão impressa ISSN 0103-507X
SALOMAO, Reinaldo et al. Guidelines for the treatment of severe sepsis and septic shock - management of the infectious agent - source control and antimicrobial treatment. Rev. bras. ter. intensiva [online]. 2011, vol.23, n.2, pp. 145-157. ISSN 0103-507X. http://dx.doi.org/10.1590/S0103-507X2011000200006.
Sepsis is a common and lethal condition that carries a substantial financial burden. In addition, it is the main cause of death in intensive care units. Early diagnosis and treatment of patients has been clearly shown to improve prognosis. Therefore, early diagnosis of the infecting agent, control of the primary infection site and the use of appropriate antibiotic therapy are fundamental to improving outcomes. This guideline reviews the available evidence in the literature concerning infection control and therapy strategies