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Fisioterapia em Movimento

versão impressa ISSN 0103-5150versão On-line ISSN 1980-5918

Resumo

CIESLAK, Fabrício et al. Physiological responses in obese adolescents submitted to bronchial provocation with hypertonic saline. Fisioter. mov. [online]. 2013, vol.26, n.2, pp.259-269. ISSN 0103-5150.  https://doi.org/10.1590/S0103-51502013000200003.

INTRODUCTION: The bronchial hyperresponsiveness is the response of increased physiological protective mechanisms in the airways of atopic and non-atopic individuals. Furthermore, the magnitude of hyperresponsiveness influences provider submits with the degree of obesity. OBJECTIVE: To evaluate the physiological responses in obese adolescents undergoing bronchial hyperresponsiveness to hypertonic saline. MATERIALS AND METHODS: Cross-sectional and correlation study consisted of 15 obese adolescents of both genders. The diagnosis of asthma was made by clinical history and ISAAC, and obesity as BMI above 95th percentile. We used the bronchial provocation test by hypertonic saline for the assessment of bronchial hyperresponsiveness, considering positive a decrease in forced expiratory volume in one second (FEV1) > 15% of pre-saline and the intensity of bronchial hyperresponsiveness was calculated as the percentage fall maximum of FEV1 (% FallmáxFEV1). We used the independent T or Mann-Whitney U test and Spearman's rho correlation (p < 0.05). RESULTS: There were no significant differences between asthmatics and non-asthmatics for anthropometric, spirometric, lipid and hemodynamic variables. There were positive correlations and significant differences between the % FallmáxFEV1 with BMI (p = 0.040) and BMI Z-score (p = 0.028). There were detected negative correlations with significant differences for FallmáxFEV1 and leukocytes (p = 0.005) and the % FallmáxFEV1 with dehydropiandrosterone sulfate (p = 0.032). CONCLUSION: It can be concluded that obese adolescents have bronchial hyperresponsiveness presented spirometric changes that are associated with systemic inflammation of obesity.

Palavras-chave : Adolescents; Bronchial provocation tests; Obesity.

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