Brazilian Dental Journal
versão impressa ISSN 0103-6440
COSTA JUNIOR, Edson Dias; SOUZA-FILHO, Francisco José de e BARBOSA, Sérgio Valmor. Tissue reactions to a component of root canal system bacteria: lipoteichoic acid. Braz. Dent. J. [online]. 2003, vol.14, n.2, pp. 95-98. ISSN 0103-6440. http://dx.doi.org/10.1590/S0103-64402003000200004.
Lipoteichoic acid (LTA), present in Gram-positive microorganisms, has physiochemical characteristics that allow it to act as an immunogen. Due to polymicrobial characteristics of root canal infections, LTA can participate in the development of periapical disease. The reaction of the rat subcutaneous tissue to Teflon tube implants, filled with Fibrinol soaked in lipoteichoic acid (concentration of 150 µg/ml), was observed. Lipoteichoic acid provoked an inflammatory tissue reaction.
Palavras-chave : lipoteichoic acid; tissue reaction; Gram-positive microorganisms.