Reynolds et al. (71) |
USA |
2 (premolar) |
18 months |
TAP |
GMTA |
_ |
Visual |
Only one tooth shown a little discoloration in the region of cervical of crown |
Kim et al. (4) |
Korea |
1 (incisor) |
8 months |
TAP |
GMTA |
Sodium perborate |
Visual |
After the use of intracanal medication was observed discoloration. Dental bleaching result in an improve of color, but not returned to original color |
Petrino et al. (88) |
USA |
4 (incisor) 2 (premolar) |
11 months |
TAP |
WMTA |
_ |
Visual |
Was observed discoloration in one tooth (after 10 days of treatment) |
Torabinejad et al. (17) |
USA |
1 (premolar) |
5.5 months |
TAP |
GMTA |
- |
Visual |
Crown of revascularized tooth presented discoloration |
Cehreli et al. (77) |
Turkey |
2 (incisor) |
18 months |
Ca(OH)2
|
GMTA |
- |
visual |
Did not observe tooth discoloration after 18 months; Dental necrosis was caused due trauma. |
Dabbagh et al. (7) |
Canada |
18 (incisor and premolar) |
24 months |
TAP TAP/cefaclor |
WMTA |
_ |
Visual |
Was observed color alterations in one tooth |
Gelman et al. (89) |
USA |
1 (central incisor) |
11 months |
TAP |
WMTA |
- |
Visual |
Grayish discoloration was observed two weeks after the star of triple antibiotic past use |
Narayana et al. (91) |
USA |
1 (NR ) |
12 months |
TAP |
WMTA |
- |
Visual |
Discoloration did not observe in the period of follow-up |
Nosrat et al. (82) |
USA |
2 (incisor) |
72 months |
TAP |
GMTA |
_ |
Visual |
The crowns showed moderate discoloration in the final of treatment |
Miller et al. (87) |
USA |
1 (incisor) |
18 months |
TAP |
WMTA |
_ |
Visual |
Little change color were observed in the cervical crown |
Becerra et al. (92) |
Colombia |
1 (premolar) |
24 months |
TAP |
WMTA |
- |
Visual |
Discoloration was observed |
Kottoor et al. (90) |
India |
1 ( incisor) |
5 years |
TAP |
WMTA |
- |
visual |
Discoloration was not observed; the authors attributing it due the use of white MTA |
McTigue et al. (9) |
USA |
29 (incisor) 3 (premolar) |
51 months |
TAP AP/ clind. |
GMTA and WMTA |
Bleaching with sodium perborate and hydrogen peroxide 10% |
Visual |
In 14 teeth were observed tooth discoloration during the treatment. Dental bleaching was able to whiten the teeth satisfactory |
Nosrat et al. (83) |
USA |
1 (incisor) |
31 months |
TAP |
WMTA |
Bleaching with sodium perborate |
Visual |
Gradual discoloration was observed at the end of treatment |
Wang et al. (18) |
China |
2 (premolar) |
18 vmonths |
TAP |
WMTA |
- |
Visual |
Both teeth presented discoloration |
Bezgin et al. (6) |
Turkey |
2 (premolar) |
12 months |
TAP / Cefaclor |
WMTA |
- |
Visual |
No discoloration was observed. Teeth were sealed with dentin bonding |
Guven Polat et al. (75) |
Turkey |
1 (premolar) |
24 months |
TAP / tetra |
GMTA |
- |
Visual |
Did not observe tooth discoloration |
Kahler et al. (8) |
Australia |
16 (incisor and premolar) |
18 months or more |
TAP / Amox. |
GMTA |
- |
Visual |
Ten of 16 teeth presented discoloration |
Kaya-Buyukbayram et al. (85) |
Turkey |
1 (Incisor) |
20 months |
Ca(OH)2 and TAP |
GMTA |
- |
Visual |
Authors reported discoloration due to MTA and TAP |
Lin et al. (86) |
Italy |
1 (incisor) |
16 months |
TAP |
GMTA |
- |
Visual |
MTA caused crown discoloration |
Nagata et al. (69) |
Brazil |
23 (incisor) |
15 months |
TAP or Ca(OH)2 + Chlorhexidine 2% |
WMTA |
_ |
Visual |
Tooth discoloration was observed in 10 of 12 teeth treated with TAP and in 3 of 11 treated with Ca(OH)2
|
Bezgin et al. (70) |
Turkey |
20 (premolar and incisor) |
18 months |
TAP / CEF |
WMTA |
- |
Visual |
Authors related that discoloration was not due antibiotic, but by MTA. 12 cases from 20 presented teeth discoloration; The author report perform the seal of dentinal walls with bonding agent to avoid the discoloration |
Park et al. (74) |
Korea |
2 (premolar) |
_ |
TAP/amox. |
GMTA |
_ |
Visual |
After 12 months of treatment the teeth presented crown discoloration |
Nagata et al. (78) |
Brazil |
1 (incisor) |
16 |
Ca(OH)2
|
WMTA |
- |
Visual |
Tooth discoloration did not observed in the follow-ups |
Sachdeva et al. (93) |
India |
1 (incisor) |
36 months |
TAP |
WMTA |
- |
Visual |
The tooth presented further discoloration after intracanal medications |
Santiago et al. (16) |
Brazil |
5 (incisor) |
15 months |
TAP |
GMTA |
_ |
Visual |
All teeth presented color changes in different levels |
Silva et al. (76) |
USA |
1 (incisor) |
36 months |
Ca(OH)2
|
WMTA |
_ |
Visual |
The teeth presented little discoloration |
Wang et al. (95) |
China |
2 (premolar) |
30 |
TAP |
WMTA |
- |
Visual |
Authors reported sings of tooth discoloration |
Asgary et al. (79) |
Iran |
2 (Incisor) |
36 months |
Calcium hydroxide / TAP |
Calcium-enriched mixture |
- |
Visual |
No discoloration was observed in both teeth treated with calcium hydroxide or TAP |
Chaniotis (13) |
Greece |
1 (incisor) |
24 months |
_ |
WMTA |
_ |
Visual |
Crown discoloration was observed |
Cho et al. (11) |
Korea |
1 (canine) |
24 months |
DAP / ciprofloxacin and metronidazole |
GMTA |
- |
Visual |
Bluish-gray discolorations was observed after the application of paste |
Plascencia et al. (14) |
Mexico |
1 (Incisor) |
32 Months |
Ca(OH)2
|
WMTA |
- |
Visual |
Mild discoloration was observed |
Ray et al. (10) |
USA |
1 (incisor) |
36 months |
DAP ciprofloxacin and metronidazole |
GMTA |
- |
visual |
The tooth presented discoloration |
She et al. (80) |
China |
1 (premolar) |
66 Months |
Ca(OH)2
|
GMTA |
- |
Visual |
It was observed discoloration in cervical region |
Wang et al. (94) |
China |
2 (premolar) |
17/18 months |
TAP |
WMTA |
- |
visual |
It was observed discoloration |
Bakhtiar et al. (72) |
UK |
4 (incisor) |
18 months |
TAP/cefaclor |
Biodentine |
- |
Visual |
Discoloration was observed in 4 of 4 cases. Besides, Dentin walls of the pulp chamber were sealed with bonding. |
Chan et al. (73) |
Canada |
28(Main incisor) |
30 months |
TAP/cefaclor |
GMTA |
- |
Visual |
Discoloration was observed in 16 of 28 teeth evaluated. Also, the discoloration occurs only in teeth with traumatized previously. |
Timmerman et al. (81) |
Australia |
1 (incisor) |
36 months |
Ca(OH)2
|
GMTA |
- |
Visual |
The tooth did not presented discoloration |