SciELO - Scientific Electronic Library Online

vol.39 issue1Prevalence of Salmonella sp. in swine slaughtered at Mato Grosso state, BrazilType C botulism in turkeys in Minas Gerais, Brazil author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Ciência Rural

Print version ISSN 0103-8478On-line version ISSN 1678-4596


FREITAS, Theonys Diógenes et al. Production and characterization of monoclonal antibodies against Clostridium perfringens Type D epsilon toxin. Cienc. Rural [online]. 2009, vol.39, n.1, pp.269-271.  Epub Sep 04, 2008. ISSN 0103-8478.

Clostridium perfringens type D is the aetiological agent of enterotoxemia in ruminants. The disease is caused by epsilon toxin characterized by cardiac, pulmonary, kidney and brain edema. Monoclonal antibodies were produced by using myeloma cell line P3-X63-Ag8 653 fused with spleen cells from Balb/c mice, immunized with epsilon toxoid of C. perfringens type D. Six hybrids were established secreting monoclonal antibodies of the IgM class and IgG3 subclass.

Keywords : Clostridium perfringens; epsilon toxin; monoclonal antibodies.

        · abstract in Portuguese     · text in Portuguese     · Portuguese ( pdf epdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License