Resumo

MALMONGE, Sonia M  e  ZAVAGLIA, Cecília A. C. PolyHEMA hydrogels for repairs or articular cartilage defects: 1 – systhesis and mechanical characterization. Polímeros [online]. 1997, vol.7, n.2, pp.22-29. ISSN 0104-1428.  https://doi.org/10.1590/S0104-14281997000200004.

The purpose of this work was the study of poly-2-hydroxy-ethyl-metacrylate (polyHEMA) as a biomaterial for the repair of articular cartilage defects. Improvement of mechanical properties were studied by two distincts routes: changes in cross-link density of the gels and the synthesis of cellulose acetate and poly-methyl metacrylate-acrylic acid copolymers semi interpenetrating blends. The hydrogels were synthesized by thermal polymerization and characterized by swelling behaviour in 0.15 Mol.L-1 NaCl and by creep indentation tests. The results showed that the blending of PolyHEMA with poly-methyl metacrylate-acrylic acid copolymers significantly improved the mechanical properties of hydrogels without changes in their swelling behavior.

Palavras-chave : Poly(2 hydroxy ethyl methacrylate); indententation; articular cartilage regeneration.

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