SciELO - Scientific Electronic Library Online

 
vol.19 número2Monitoramento in situ e em tempo real de variáveis morfológicas do poli(cloreto de vinila) usando espectroscopia NIRElucidação parcial da estrutura de aminoglucanooligossacarídeos (AGO's) produzidos enzimaticamente índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

Compartilhar


Polímeros

versão impressa ISSN 0104-1428versão On-line ISSN 1678-5169

Resumo

RUBIRA, Adley F. et al. Morphology of temperature-sensitive and ph-responsive ipn-hydrogels for application as biomaterial for cell growth. Polímeros [online]. 2009, vol.19, n.2, pp.105-110. ISSN 1678-5169.  https://doi.org/10.1590/S0104-14282009000200006.

In the present investigation, hydrogels with pH-responsive and temperature-sensitive properties were obtained by formation of alginate-Ca network inside the PNIPAAm network resulting in an interpenetrated network system (IPN). From scanning electron microscopy (SEM) images and water uptake (WU) tests one observed that IPN hydrogels exhibited a drastic shrinking when heated above 30-35 ºC. The shrinking resulted in decreased average pore size, thus affect the hydrogel morphology significantly. In the pH range studied, IPN hydrogels showed significant pH dependence, which was attributed to the charged alginate groups. The results indicated that the pH-responsiveness and temperature-dependence of alginate and PNIPAAm, respectively, were preserved in IPN hydrogels. In addition, such hydrogels become less deformable when subjected to compressive stress. These hydrogels presented porous morphology that may be tuned by controlling the temperature, and this makes them attractive for applications as biomaterial in cell growth.

Palavras-chave : Hydrogels; temperature-sensitivity; pH-responsive; morphology; cell growing.

        · resumo em Português     · texto em Português     · Português ( pdf )

 

Creative Commons License Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons