Print version ISSN 0104-1428
SEVERINO, Patrícia; SANTANA, Maria Helena A.; MALMONGE, Sônia M. and SOUTO, Eliana B.. Polymers for drug delivery systems formulations. Polímeros [online]. 2011, vol.21, n.5, pp.361-368. Epub Nov 23, 2011. ISSN 0104-1428. http://dx.doi.org/10.1590/S0104-14282011005000061.
The different carrier systems have shown therapeutic potential for a wide variety of drugs, satisfying multiple requirements, such as prevention of rapid elimination, reducing toxicity, promoting stabilization, optimization of metabolism, drug delivery and defense mechanisms. However, it has been recognized several other challenges associated with the specific release of actives in drug delivery. Therefore, to overcome chemical and biological obstacles, the selection of the polymer used to prepare the transport system is crucial. This paper presents a report on the main natural and synthetic polymers used in the preparation of drug carrier systems in vivo.
Keywords : Synthetic polymers; natural polymers; carrier of drugs.