SciELO - Scientific Electronic Library Online

 
vol.44 issue4Risk factors for esophageal cancer in Rio Grande do Sul, Brazil author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Revista da Associação Médica Brasileira

Print version ISSN 0104-4230

Abstract

MOREIRA, M. et al. The effect of bloodstream hospital infection by Staphylococcus aureus resistant to methicillin on the mortality and the length of hospitalization. Rev. Assoc. Med. Bras. [online]. 1998, vol.44, n.4, pp. 263-268. ISSN 0104-4230.  http://dx.doi.org/10.1590/S0104-42301998000400002.

OBJECTIVES: To identify the attributed mortality rate of bloodstream hospital infection by Staphylococcus aureus resistant to methicillin (MRSA) and its effect on length of hospital stay. DESIGN:Case-control study SETTING: Hospital São Paulo da Universidade Federal de São Paulo, a 660-bed, tertiary-care teaching hospital in São Paulo, Brazil. PATIENTS: Seventy one adults patients with hospital-acquired MRSA bacteremia diagnosed between January 1, 1991, and September 30, 1992, and 71 MRSA-free controls were matched by the following criteria: age, sex, underlying disease, surgical procedure, same risk time and admissiom date. RESULTS: The incidence of patients with hospital sepsis by MRSA accounted for 73.22% of the patients with hospital bloodstream infection by Staphylococcus aureus . The mortality rate of the cases was 56.33 (40/71) and 11.26 (8/71) of the controls. The attributable mortality rate was 45.07% (OR=17.0; IC 95%=3.58 ¾ 202.26; p=0.000001). The length of hospital stay median time was of 32.55 days for the cases and 29.75 for the controls (p = 0.32). CONCLUSION: A high level of sepsis by MRSA was observed in all the Staphylococcus aureus bacteremia. The bloodstream hospital infection by MRSA itself does provide a high level of mortality independently from the patients base disease, without however, increasing their hospital length of stay.

Keywords : Sepsis; Mortality; Staphylococcus aureus; Cross infection.

        · abstract in Portuguese     · text in Portuguese     · pdf in Portuguese