SciELO - Scientific Electronic Library Online

vol.50 issue2Hypertension in women: study in mothers of students from Jaboatão dos Guararapes, Pernambuco, BrazilIdentification of insulinomas by endoscopic ultrasonography author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Revista da Associação Médica Brasileira

Print version ISSN 0104-4230On-line version ISSN 1806-9282


VIANA, Ana Carolina de Sá; LIBERATORE JUNIOR, Raphael Del Roio  and  GOLONI BERTOLLO, Eny Maria. Puberty and growth in children and adolescents with neuro fibromatosis type 1. Rev. Assoc. Med. Bras. [online]. 2004, vol.50, n.2, pp.163-166. ISSN 0104-4230.

BACKGROUND: This study evaluates anthropometric and pubertal development parameters in children and adolescents with sporadic and familial occurrence of neurofibromatosis type 1 (NF-1). METHODS: The study involved 23 patients (15 boys, 8 girls) with sporadic (n=12) and familial NF-1(7 affected mothers and 4 fathers), with average age of 12 years (range 5-20 years). All patients answered to a standard questionnaire including family and personal data and, following, they underwent systematized physical examination, with special attention to anthropometric data, dermatologic and pubertal stage according to Tanner's criteria evaluation. RESULTS: Short stature was detected in a 17 year-old patient, 148.5cm height, with score Z of -4.16 and being the even outside of the family conduit. Three male patients had head circumference above of + 2DP from on average for the age. It was not found no case of precocious or delayed puberty . CONCLUSIONS: In our study, do not we find significant alterations regarding the stature and pubertal development.

Keywords : Neurofibromatosis type 1; Short stature; Puberty; Growth.

        · abstract in Portuguese     · text in Portuguese     · Portuguese ( pdf epdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License