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Revista da Associação Médica Brasileira

versão impressa ISSN 0104-4230versão On-line ISSN 1806-9282

Resumo

KALIKS, Rafael A.  e  DEL GIGLIO, Auro. Management of advanced prostate cancer. Rev. Assoc. Med. Bras. [online]. 2008, vol.54, n.2, pp.178-182. ISSN 0104-4230.  http://dx.doi.org/10.1590/S0104-42302008000200025.

Geriatricians and general practitioners often follow patients with metastatic prostate cancer. The epidemiology and basic treatment principles of metastatic prostate cancer are discussed aiming to update the topic for the non-oncologist. Hormone manipulation remains the basis of treatment, usually up to a second line of therapy. Selected cases are treated successfully with intermittent androgen ablation. When new hormone-independent clones arise, chemotherapy should be added to therapy that confers improved survival as well as better quality of life when based on taxanes. In specific situations, additional measures such as bisphosphonates and radiation therapy should be included in the treatment. As a rule, the public health system makes available the necessary medication to ensure treatment for the vast majority of patients in Brazil.

Palavras-chave : Prostatic neoplasms [therapy]; Hormones [therapeutic use]; Hormonal antineoplastic agents; Drug therapy; Epidemiology.

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