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Revista da Associação Médica Brasileira

Print version ISSN 0104-4230On-line version ISSN 1806-9282


NORONHA NETO, Carlos; SOUZA, Alex Sandro Rolland de; MORAES FILHO, Olímpio Barbosa de  and  NORONHA, Adriana Mota Bione. Validation of ultrasound diagnosis of fetal anomalies at a reference center in Pernambuco. Rev. Assoc. Med. Bras. [online]. 2009, vol.55, n.5, pp.541-546. ISSN 0104-4230.

OBJECTIVE: To validate ultrasound diagnoses of fetal anomalies made in a Fetal Medicine Center in Pernambuco. METHODS: A cross sectional study was performed to validate the diagnosis test, including all high risk pregnant women submitted to obstetrical morphological ultrasound at the "Instituto de Medicina Integral Professor Fernando Figueira (I.M.I.P.)", from March 2002 to March 2006. Prenatal diagnosis was confirmed after birth. Socio demographic characteristics and pre and postnatal frequencies of fetal anomalies were the variables studied. Agreement between pre and postnatal diagnoses from congenital anomalies were evaluated with the Kappa indicator. Youden's test was applied to validate prenatal ultrasound diagnoses. RESULTS: Nine hundred and eighty nine patients were eligible. After evaluation of inclusion and exclusion criteria 457 patients were included in study. The average maternal age was 24.8 + 6.5 years. Fetal anomaly diagnoses postnatal were confirmed in 257 (56.2%) pregnant women. Prenatal ultrasound diagnosis of fetal anomalies disclosed 96% of sensibility and 79% of specificity, good agreement (K=0.76) between pre and postnatal diagnoses when compared to postnatal results and good diagnostic validity (Y=0.75). CONCLUSION: Prenatal diagnoses of fetal anomalies at a Fetal Medicine center in Pernambuco demonstrate good sensibility, specificity, agreement pre and postnatal and good diagnostic validity.

Keywords : Ultrasonography; Sensitivity and specificity; Congenital; Hereditary and neonatal diseases and anomalies prenatal diagnosis.

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