Abstract

FERREIRA, Flávia Regina; NASCIMENTO, Luiz Fernando Costa  and  ROTTA, Osmar. Risk factors for nonmelanoma skin cancer in Taubaté, SP: a case-control study. Rev. Assoc. Med. Bras. [online]. 2011, vol.57, n.4, pp. 431-437. ISSN 0104-4230.  http://dx.doi.org/10.1590/S0104-42302011000400018.

OBJECTIVE: To identify factors associated with non-melanoma skin cancer in the city of Taubaté, São Paulo, Brazil. METHODS: Hospital-based case-control study with individuals residing in Taubaté, treated between January 2005 and December 2006. The subjects were matched 1:1 according to gender and age. Age, gender, phototype, European descent, time of residence, sun exposure, time (in years), number of hours and time of occupational and non-occupational sun exposure, photoprotection, family history and photodamage were independent variables. A hierarchical logistic regression was used at three levels. The model adjustment was performed using the Hosmer-Lemeshow test and its accuracy was verified by ROC curve. The significance level was p < 0.05. RESULTS: There were 132 cases and 132 controls. Phototype with OR = 3.14 (95% CI 1.79-5.49), hours of occupational 1.76 (1.04-2.99) and non-occupational sun exposure 1.80 (0.98-3.29) and family history 2.10 (1.13-3.93) were the variables in the final model. Hosmer-Lemeshow test, p = 0.97. Accuracy 70% (95% CI 63-76). CONCLUSION: We concluded that fair skin, family history and occupational and non-occupational sun exposure were associated with non-melanoma skin cancer in Taubaté-São Paulo.

Keywords : Skin neoplasms; risk factors; multivariate analysis; neoplasms, basal cell; neoplasms, squamous cell.