| Le Gal et al.1010 Le Gal G, Prins AM, Righini M, Bohec C, Lacut K, Germain P, et al. Diagnostic value of a negative single complete compression ultrasound of the lower limbs to exclude the diagnosis of deep venous thrombosis in pregnant or postpartum women: a retrospective hospital-based study. Thromb Res. 2006; 118(6):691-7.
|
2006 |
Retrospective |
Pregnant and postpartum women; mean age of all women was 29 ± 5 years; mean age of pregnant women was 29 ± 5 years and mean age of postpartum women 30 ± 5 years
Number of participants: 8 in 1st trimester, 29 in 2nd trimester, 43 in 3rd trimester, and 82 in postpartum |
The US compression test was considered negative when the veins were fully compressible, with no thrombus visualized, and when the Doppler signal at the common femoral vein was phasic during spontaneous respiration |
Several specialists including senior and junior examiners |
12 weeks |
44 out of the 162 had positive test results; 118 had negative test results and 107 out of them were found during the follow-up time remaining negative |
118 participants completed the follow-up
Only women with negative results were included
Three participants who received heparin were excluded from analysis |
| Ratiu et al.1111 Ratiu A, Navolan D, Spatariu I, Biris M, Miculita M, Motoc A. Diagnostic value of a negative single color duplex ultrasound in deep vein thrombosis suspicion during pregnancy. Rev Med Chir Soc Med Nat Iasi. 2010; 114(2):454-6.
|
2010 |
Prospective |
87 consecutive pregnant women with clinical suspicion of DVT; mean age was 24.68 ± 3.99 years; gestational age was 35.32 ± 2.81 weeks |
Positive results were based on lack of complete luminal obliteration following compression, flow void on color Doppler scans and lack of flow detection on spectral analysis |
Not reported |
6 weeks |
30 (34.48%) had positive test results and two (2.29%) had a high clinical suspicion of DVT; 55 (63.21%) had negative test results and repeated the US exam after 7 days remaining negative |
Participants who were positive onUS or negative on US but had high clinical probability of DVT underwent venography and were excluded
12 participants who were lost to follow-up were excluded from analysis |
| Torkzad et al.1212 Torkzad MR, Bremme K, Hellgren M, Eriksson MJ, Hagman A, Jörgensen T, et al. Magnetic resonance imaging and ultrasonography in diagnosis of pelvic vein thrombosis during pregnancy. Thromb Res. 2010; 126(2):107-12.
|
2010 |
Prospective |
27 pregnant women with diagnosed DVT from 23rd gestational week until 37th gestational week; mean age of the patients was 30.2 years (range 21-46), the average gestational age at DVT was 29.5 (range 23-39) weeks |
Direct examination of the thrombus based on gray-scale ultrasound, compression technique and color flow Doppler, and indirect imaging based on flow measurements with spectral and color-Doppler |
Specialists in clinical physiology with 15-17 years of experience in vascular ultrasound |
Not reported |
Three out of the 27 cases (11.5%) of DVT in the pelvic veins were missed on ultrasound but detected by magnetic resonance |
Participants received heparin
Magnetic resonance was used in this study to see the agreement between diagnostic tests |
| Le Gal et al.1313 Le Gal G, Kercret G, Ben Yahmed K, Bressollette L, Robert-Ebadi H, Riberdy L, et al.; EDVIGE Study Group. Diagnostic value of single complete compression ultrasonography in pregnant and postpartum women with suspected deep vein thrombosis: prospective study. BMJ. 2012; 344:e2635.
|
2012 |
Prospective |
Pregnant and postpartum women; mean age of all women was33 years (interquartile range 28-37 years)
Number of participants: 20 in 1st trimester, 51 in 2nd trimester, 96 in 3rd trimester, and 43 in postpartum |
Deep-vein thrombosis was diagnosed with lack of compressibility of a deep vein and, for the iliac vein, in the absence of Doppler flow or direct visualization of a thrombus |
Vascular medicine specialists with at least 10 years of experience in vascular ultrasound imaging |
12 weeks |
22 out of the 210 participants (10.5%) had positive test results; two out of the 177 who had negative test results were positive during follow-up |
Participants who were positive on US were excluded
10 participants who received heparin were excluded from analysis
One participant who was lost to follow-up was excluded from analysis |
