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Functional decline in the elderly with MCI: Cultural adaptation of the ADCS-ADL scale

Declínio funcional em idosos com comprometimento cognitivo leve: adaptação cultural da escala ADCS-ADL.

Summary

Objective:

Translate, transcultural adaptation and application to Brazilian Portuguese of the Alzheimer’s Disease Cooperative Study - Activities of Daily Living (ADCS-ADL) scale as a cognitive screening instrument.

Method:

We applied the back translation added with pretest and bilingual methods. The sample was composed by 95 elderly individuals and their caregivers. Thirty-two (32) participants were diagnosed as mild cognitive impairment (MCI) patients, 33 as Alzheimer’s disease (AD) patients and 30 were considered as cognitively normal individuals.

Results:

There were only little changes on the scale. The Cronbach alpha coefficient was 0.89. The scores were 72.9 for control group, followed by MCI (65.1) and by AD (55.9), with a p-value < 0.001. The ROC curve value was 0.89. We considered a cut point of 72 and we observed a sensibility of 86.2%, specificity of 70%, positive predictive value of 86.2%, negative predictive value of 70%, positive likelihood ratio of 2.9 and negative likelihood ratio of 0.2.

Conclusion:

ADCS-ADL scale presents satisfactory psychometric properties to discriminate between MCI, AD and normal cognition.

Keywords:
mild cognitive impairment; Alzheimer’s disease; activities of daily living

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