SciELO - Scientific Electronic Library Online

 
vol.65 issue3Critical analysis of the classic indications for myocardial revascularizationMucosal vitiligo in angles of the mouth: clinical and fluorescence aspects author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

Share


Revista da Associação Médica Brasileira

Print version ISSN 0104-4230On-line version ISSN 1806-9282

Abstract

CABRAL, Catia et al. Eosinophilic fasciitis: an atypical presentation of a rare disease. Rev. Assoc. Med. Bras. [online]. 2019, vol.65, n.3, pp.326-329.  Epub Apr 11, 2019. ISSN 0104-4230.  https://doi.org/10.1590/1806-9282.65.3.326.

Eosinophilic fasciitis, or Shulman's disease, is a rare disease of unknown etiology. It is characterized by peripheral eosinophilia, hypergammaglobulinemia, and high erythrocyte sedimentation rate. The diagnosis is confirmed by a deep biopsy of the skin. The first line of treatment is corticotherapy.

We present a rare case of eosinophilic fasciitis in a 27-year-old woman with an atypical presentation with symmetrical peripheral edema and a Groove sign. The patient responded well to treatment with corticosteroids at high doses and, in this context, was associated with hydroxychloroquine and azathioprine. After two and a half years, peripheral eosinophilia had increased, and more of her skin had hardened. At that time, the therapy was modified to include corticoids, methotrexate, and penicillamine. It is of great importance to publicize these cases that allow us to gather experience and better treat our patients.

Keywords : Fasciitis; Eosinophils; Eosinophilia; Edema/etiology.

        · abstract in Portuguese     · text in English     · English ( pdf )